RESUMO
Se ha evaluado la eficacia y tolerancia del cambio a monoterapia con fumarato de quetiapina (FQ) en la esquizofrenia resistente al tratamiento previo con otros antipsicóticos, uno de ellos atípico. El tratamiento con FQ se mantuvo durante8 semanas. Las puntuaciones de la PANSS mejoraron al menos un 40 % en este periodo. El FQ fue bien tolerados in la presencia de efectos adversos relevantes. El cambio a FQ en estos pacientes puede por tanto considerarse como óptimo en respuesta y tolerancia (AU)
We assessed the efficacy and tolerance of switching to monotherapy with quetiapine fumarate (QF) in treatment resistant schizophrenia with other antipsychotics, including atypical ones. QF treatment was maintained for 8 weeks. The PANSS scores improved at least 40% over this period. QF was well tolerated without the presence of serious adverse effects. Switching to QF in these patients may therefore be considered as optimal in response and tolerance (AU)
Assuntos
Humanos , Masculino , Adulto , Esquizofrenia/diagnóstico , Esquizofrenia/patologia , Psicologia/ética , Psiquiatria/educação , Psiquiatria/história , Antipsicóticos , Antipsicóticos/provisão & distribuição , Antipsicóticos/metabolismo , Antipsicóticos/normas , Esquizofrenia/complicações , Esquizofrenia/enfermagem , Esquizofrenia/terapia , Psiquiatria/métodos , Psiquiatria/estatística & dados numéricos , Psiquiatria/tendênciasRESUMO
We assessed the efficacy and tolerance of switching to monotherapy with quetiapine fumarate (QF) in treatmentresistant schizophrenia with other antipsychotics, including atypical ones. QF treatment was maintained for 8 weeks. The PANSS scores improved at least 40% over this period. QF was well tolerated without the presence of serious adverse effects. Switching to QF in these patients may therefore be considered as optimal in response and tolerance. Key words: Schizophrenia, Treatment-resistant, Antipsychotics, Quetiapine fumarate.
